As an example, playing the very high variance slot game Isis has cost me a lot of money down the years, but in 2008 I hit 5 scatters in the free spins, betting an unusually high $12.50 a spin for a massive $49,300! Horses for courses, rough with the smooth, slots are games of chance - the key is to know when to cash out! Examples of high variance slots could be those with many 'Wild' symbols that can line up to give huge numbers of line wins within a single spin.